{"id":18846,"date":"2021-06-08T12:14:32","date_gmt":"2021-06-08T11:14:32","guid":{"rendered":"https:\/\/opa.org.uk\/?page_id=18846"},"modified":"2021-06-08T12:14:32","modified_gmt":"2021-06-08T11:14:32","slug":"evolution-of-gastrectomy-for-cancer-over-30-years-changes-in-presentation-management-and-outcomes","status":"publish","type":"page","link":"https:\/\/opa-old.voidappsdev.uk\/?page_id=18846","title":{"rendered":"Evolution of gastrectomy for cancer over 30-years: Changes in presentation, management, and outcomes"},"content":{"rendered":"
\n

Evolution of gastrectomy for cancer over 30-years: Changes in presentation, management, and outcomes<\/h1>\n

Background<\/h3>\n

Gastric cancer has seen a considerable change in management, and outcomes for the past 30 years. Historically, the overall prognosis has been regarded as poor. However, the use of multimodal treatment, and integration of enhanced recovery pathways have improved short and long-term outcomes. The aim of this study was to evaluate the changing trends in presentation, management, and outcomes for patients undergoing surgical treatment for gastric cancers over 30 years.<\/p>\n<\/div>\n

\n

Methods<\/h3>\n

Data from consecutive patients undergoing\u00a0gastrectomy<\/a>\u00a0with curative intent for\u00a0gastric adenocarcinoma<\/a>\u00a0between 1989 and 2018 from a single-center, high-volume unit were reviewed. Presentation method, management strategies and outcomes were reviewed. Patients were grouped into successive 5-year cohorts for comparison and evaluation of changing trends.<\/p>\n<\/div>\n

\n

Results<\/h3>\n

Between 1989 and 2018, 1,162 patients underwent gastrectomy with curative intent for cancer. Median age was 71 years (interquartile range, 63\u221276 years) and 763 (66%) were male. Patient presentation changed with\u00a0epigastric discomfort<\/a>\u00a0now the most common presentation (67%). An improvement in overall complications from 54% to 35% (P<\/em>\u00a0= .006) and mortality from 8% to 1% (P<\/em>\u00a0< .001) was seen over the time period and overall survival improved from 28 months to 53 months (P<\/em>\u00a0< .001).<\/p>\n<\/div>\n

\n

Conclusion<\/h3>\n

Both short-term and long-term outcomes have significantly improved over the 30 years studied. The reasons for this are multifactorial and include the use of perioperative chemotherapy, the introduction of an enhanced recovery pathway, and improved\u00a0preoperative assessment<\/a>\u00a0of patients through a multidisciplinary input.<\/p>\n

This article is from Science Direct – https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0039606021000787<\/a><\/em><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Evolution of gastrectomy for cancer over 30-years: Changes in presentation, management, and outcomes Background Gastric cancer has seen a considerable change in management, and outcomes for the past 30 years. Historically, the overall prognosis has been regarded as poor. However, the use of multimodal treatment, and integration of enhanced recovery pathways have improved short and long-term outcomes. The aim of this study was to evaluate the changing trends in presentation, management, and outcomes for patients undergoing surgical treatment for gastric cancers over 30 years. Methods Data from consecutive patients undergoing\u00a0gastrectomy\u00a0with curative intent for\u00a0gastric adenocarcinoma\u00a0between 1989 and 2018 from a single-center, high-volume unit were reviewed. Presentation method, management strategies and outcomes were reviewed. Patients were grouped into successive 5-year cohorts for comparison and evaluation of changing trends. Results Between 1989 and 2018, 1,162 patients underwent gastrectomy with curative intent for cancer. Median age was 71 years (interquartile range, 63\u221276 years) and 763 (66%) were male. Patient presentation changed with\u00a0epigastric discomfort\u00a0now the most common presentation (67%). An improvement in overall complications from 54% to 35% (P\u00a0= .006) and mortality from 8% to 1% (P\u00a0< .001) was seen over the time period and overall survival improved from 28 months to 53 months (P\u00a0< […]<\/p>\n","protected":false},"author":4,"featured_media":0,"parent":18294,"menu_order":31,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-18846","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"\nEvolution of gastrectomy for cancer over 30-years: Changes in presentation, management, and outcomes - The OPA<\/title>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Evolution of gastrectomy for cancer over 30-years: Changes in presentation, management, and outcomes - The OPA\" \/>\n<meta property=\"og:description\" content=\"Evolution of gastrectomy for cancer over 30-years: Changes in presentation, management, and outcomes Background Gastric cancer has seen a considerable change in management, and outcomes for the past 30 years. 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