{"id":15996,"date":"2020-08-18T13:01:17","date_gmt":"2020-08-18T12:01:17","guid":{"rendered":"http:\/\/opa.org.uk\/?p=15996"},"modified":"2021-01-22T13:03:09","modified_gmt":"2021-01-22T13:03:09","slug":"can-heartburn-drugs-lead-to-vitamin-b-12-deficiency","status":"publish","type":"post","link":"https:\/\/opa-old.voidappsdev.uk\/?p=15996","title":{"rendered":"Can heartburn drugs lead to vitamin B-12 deficiency?"},"content":{"rendered":"<p>Some studies have found an association between prescription heartburn medications and increased risk of vitamin B-12 deficiency.<\/p>\n<p>Prescription medicines to treat heartburn, also called gastroesophageal reflux disease (GERD), work by suppressing stomach acid. It now appears that blocking stomach acid and other secretions may also block B-12 absorption.<\/p>\n<p>Why is this important? Vitamin B-12 deficiency has potentially serious and sometimes irreversible complications if undiagnosed and untreated. These can include dementia, disorientation, neurological damage, gait disturbance and anemia.<\/p>\n<p>Two common types of\u00a0<abbr title=\"gastroesophageal reflux disease\">GERD<\/abbr>\u00a0medicines have been associated with B-12 deficiency to varying degrees:<\/p>\n<ul>\n<li>H-2-receptor blockers.\u00a0Examples include cimetidine, famotidine and ranitidine.<\/li>\n<li>Proton pump inhibitors.\u00a0Examples include omeprazole, esomeprazole and lansoprazole.<\/li>\n<\/ul>\n<p>With either medication, the risk of B-12 deficiency was significantly increased when taken daily for two years or more, and in doses averaging more than 1.5 pills daily versus less than 0.75 pills daily.<\/p>\n<p>Does this mean that you should stop taking your heartburn medication? No. This type of study only shows that such medicines are associated with B-12 deficiency \u2014 it does not prove that the medicines cause the deficiency.<\/p>\n<p>If you&#8217;re concerned about your vitamin B-12 level, talk with your doctor. If low B-12 is an issue, ask if a lower dose of your medicine would be effective in controlling your symptoms or whether you should take a vitamin B-12 supplement.<\/p>\n<p>This article is from Mayo Clinic &#8211;\u00a0<a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/gerd\/expert-answers\/heartburn-meds-and-b12\/faq-20348628\">https:\/\/www.mayoclinic.org\/diseases-conditions\/gerd\/expert-answers\/heartburn-meds-and-b12\/faq-20348628<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Some studies have found an association between prescription heartburn medications and increased risk of vitamin B-12 deficiency&#8230;<\/p>\n","protected":false},"author":4,"featured_media":15997,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-15996","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorised"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Can heartburn drugs lead to vitamin B-12 deficiency? 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